{"id":623,"date":"2026-04-19T14:00:46","date_gmt":"2026-04-19T14:00:46","guid":{"rendered":"https:\/\/blog.vespellar.com\/crispr-cas9-%ec%9c%a0%ec%a0%84%ec%9e%90-%ec%b9%98%eb%a3%8c-%eb%82%9c%ec%b9%98%eb%b3%91-%ec%a0%95%eb%b3%b5%ec%9d%98-%ec%84%9c%eb%a7%89%ec%9d%84-%ec%97%ac%eb%8a%94-%ec%a0%95%eb%b0%80-%ec%9d%98%ed%95%99\/"},"modified":"2026-04-19T14:00:46","modified_gmt":"2026-04-19T14:00:46","slug":"crispr-cas9-%ec%9c%a0%ec%a0%84%ec%9e%90-%ec%b9%98%eb%a3%8c-%eb%82%9c%ec%b9%98%eb%b3%91-%ec%a0%95%eb%b3%b5%ec%9d%98-%ec%84%9c%eb%a7%89%ec%9d%84-%ec%97%ac%eb%8a%94-%ec%a0%95%eb%b0%80-%ec%9d%98%ed%95%99","status":"publish","type":"post","link":"https:\/\/www.vespellar.com\/blog\/crispr-cas9-%ec%9c%a0%ec%a0%84%ec%9e%90-%ec%b9%98%eb%a3%8c-%eb%82%9c%ec%b9%98%eb%b3%91-%ec%a0%95%eb%b3%b5%ec%9d%98-%ec%84%9c%eb%a7%89%ec%9d%84-%ec%97%ac%eb%8a%94-%ec%a0%95%eb%b0%80-%ec%9d%98%ed%95%99\/","title":{"rendered":"CRISPR-Cas9 \uc720\uc804\uc790 \uce58\ub8cc: \ub09c\uce58\ubcd1 \uc815\ubcf5\uc758 \uc11c\ub9c9\uc744 \uc5ec\ub294 \uc815\ubc00 \uc758\ud559\uc758 \ud000\ud140 \uc810\ud504\uc640 \uc0c1\uc6a9\ud654 \uc804\ub7b5"},"content":{"rendered":"

\ubb34\ud55c\ud55c \uac00\ub2a5\uc131\uc744 \ud488\uace0 \ub04a\uc784\uc5c6\uc774 \uc9c4\ud654\ud558\ub294 \uc0dd\uba85\uacf5\ud559 \ud601\uc2e0\uc758 \uc9c0\ud3c9\uc5d0\uc11c, \ub2e8\uc21c\ud55c \uacfc\ud559\uc801 \uc9c4\ubcf4\ub97c \ub118\uc5b4 \uc778\ub958\uc758 \uc0c8\ub85c\uc6b4 \uc2dc\ub300\ub97c \uc608\uace0\ud558\ub294 \uae30\ub150\ube44\uc801\uc778 \uc0ac\uac74\ub4e4\uc774 \uc788\uc2b5\ub2c8\ub2e4. CRISPR-Cas9 \uc720\uc804\uc790 \ud3b8\uc9d1 \uae30\uc220\uc740 \ubc14\ub85c \uadf8\ub7ec\ud55c \uac70\ub300\ud55c \ub3c4\uc57d \uc911 \ud558\ub098\ub85c, \uc815\ubc00 \uc758\ud559 \ubd84\uc57c\uc758 ‘\ud000\ud140 \uc81c\ub124\uc2dc\uc2a4’\ub97c \uc5f4\uba70 \ub09c\uce58\ubcd1\uacfc\uc758 \uc2f8\uc6c0 \ubc29\uc2dd\uc744 \uc644\uc804\ud788 \uc7ac\uc815\uc758\ud560 \uac83\uc744 \uc57d\uc18d\ud569\ub2c8\ub2e4. \uad6c\uae00 \uae00\ub85c\ubc8c \uac80\uc0c9 \uc2dc\uc7a5\uc758 \uc218\uc11d \ube44\uc988\ub2c8\uc2a4 \ubd84\uc11d\uac00\uc774\uc790 \uc791\uac00\ub85c\uc11c, \uc800\ub294 ‘\ubca0\uc2a4\ud3a0\ub77c \ub125\uc11c\uc2a4’\uc758 ‘\uc790\uc728 \uc544\uce74\uc774\ube0c’ \uc790\ub8cc\uc9d1\uc778 \uc774 \uc6d0\uace0\uc5d0\uc11c, CRISPR-Cas9\uc758 \uc7a0\uc7ac\ub825\uc744 \uc644\uc804\ud788 \uc2e4\ud604\ud560 \ubcf5\ud569\uc801\uc778 \uc0c1\uc6a9\ud654 \uc804\ub7b5\uacfc \ud55c\ub54c \ubd88\uce58\ubcd1\uc73c\ub85c \uc5ec\uaca8\uc84c\ub358 \uc9c8\ubcd1\ub4e4\uc744 \uc815\ubcf5\ud558\ub294 \ub370 \ubbf8\uce60 \uc9c0\ub300\ud55c \uc601\ud5a5\uc5d0 \ub300\ud574 \uc2ec\uce35\uc801\uc73c\ub85c \ud0d0\uad6c\ud558\uace0\uc790 \ud569\ub2c8\ub2e4.<\/p>\n

\uc0c8\ub85c\uc6b4 \uc2dc\ub300\uc758 \uc11c\ub9c9: CRISPR-Cas9\uc758 \ud601\uba85\uc801\uc778 \ud798 \uc774\ud574\ud558\uae30<\/strong><\/p>\n

CRISPR(\uaddc\uce59\uc801\uc73c\ub85c \uac04\uaca9\uc744 \ub454 \uc9e7\uc740 \ud68c\ubb38\ud615 \ubc18\ubcf5 \uc11c\uc5f4)\uacfc \uad00\ub828 \ub2e8\ubc31\uc9c8 Cas9\ub294 DNA \uc11c\uc5f4\uc744 \uc218\uc815\ud558\ub294 \ub370 \uc804\ub840 \uc5c6\ub294 \uc218\uc900\uc758 \uc815\ubc00\ub3c4, \ud6a8\uc728\uc131 \ubc0f \ub2e4\uc6a9\uc131\uc744 \uc81c\uacf5\ud558\uba70 \uc720\uc804\uc790 \ud3b8\uc9d1\uc5d0 \ud601\uba85\uc744 \uc77c\uc73c\ucf30\uc2b5\ub2c8\ub2e4. \uc774 \ubd84\uc790 ‘\uc720\uc804 \uac00\uc704’\ub294 \uacfc\ud559\uc790\ub4e4\uc774 \ud2b9\uc815 \uc720\uc804\uc790\ub97c \ud45c\uc801\uc73c\ub85c \uc0bc\uc544 DNA\ub97c \uc808\ub2e8\ud55c \ub2e4\uc74c, \uc138\ud3ec\uc758 \uc790\uc5f0\uc801\uc778 \ubcf5\uad6c \uba54\ucee4\ub2c8\uc998\uc744 \ud65c\uc6a9\ud558\uc5ec \uc720\uc804 \ubb3c\uc9c8\uc744 \uad50\uc815, \uc0bd\uc785 \ub610\ub294 \uc0ad\uc81c\ud560 \uc218 \uc788\ub3c4\ub85d \ud569\ub2c8\ub2e4. ZFN(\uc9d5\ud06c \ud551\uac70 \ub274\ud074\ub808\uc544\uc81c) \ubc0f TALEN(\uc804\uc0ac \ud65c\uc131 \uc778\uc790 \uc720\uc0ac \ub274\ud074\ub808\uc544\uc81c)\uacfc \uac19\uc740 \uc774\uc804 \uc720\uc804\uc790 \ud3b8\uc9d1 \ub3c4\uad6c\uc5d0 \ube44\ud574 \ub2e8\uc21c\ud558\uace0 \uc800\ub834\ud558\ub2e4\ub294 \uc7a5\uc810\uc740 \uc778\uac04 \uac74\uac15\uc5d0\uc11c \ub18d\uc5c5\uc5d0 \uc774\ub974\uae30\uae4c\uc9c0 \ub2e4\uc591\ud55c \ubd84\uc57c\uc758 \uc5f0\uad6c \uac1c\ubc1c\uc744 \uac00\uc18d\ud654\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\n

“CRISPR \ub274\ud074\ub808\uc544\uc81c\uc758 \ub4f1\uc7a5\uc740 DNA \ud3b8\uc9d1\uc744 \uc704\ud55c \uc27d\uace0 \ud6a8\uc728\uc801\uc774\uba70 \ub2e4\uc7ac\ub2e4\ub2a5\ud55c \ud50c\ub7ab\ud3fc\uc744 \uc81c\uacf5\ud568\uc73c\ub85c\uc368 \uc0dd\uba85\uacf5\ud559\uc744 \ubcc0\ud654\uc2dc\ucf30\uc2b5\ub2c8\ub2e4.”<\/em><\/p>\n<\/blockquote>\n

\ucd08\uae30 CRISPR-Cas9 \uc2dc\uc2a4\ud15c\uc740 \uac15\ub825\ud588\uc9c0\ub9cc DNA\uc758 \uc774\uc911 \uac00\ub2e5 \uc808\ub2e8(DSB)\uc744 \uc720\ubc1c\ud558\uc5ec \ub54c\ub54c\ub85c \uc758\ub3c4\ud558\uc9c0 \uc54a\uace0 \ubd80\uc815\ud655\ud55c \ubcc0\ud654\ub97c \ucd08\ub798\ud560 \uc218 \uc788\uc5c8\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc5fc\uae30 \ud3b8\uc9d1 \ubc0f \ud504\ub77c\uc784 \ud3b8\uc9d1\uacfc \uac19\uc740 ‘\ucc28\uc138\ub300’ CRISPR \uae30\uc220\uc758 \ub3c4\uc785\uc73c\ub85c \uc774 \ubd84\uc57c\ub294 \ube60\ub974\uac8c \ubc1c\uc804\ud588\uc2b5\ub2c8\ub2e4. \uc5fc\uae30 \ud3b8\uc9d1\uae30\ub294 DSB\ub97c \uc0dd\uc131\ud558\uc9c0 \uc54a\uace0 DNA \uc5fc\uae30\ub97c \ub2e4\ub978 \uc5fc\uae30\ub85c \uc9c1\uc811 \ubcc0\ud658\ud558\uc5ec \uc815\ubc00\ud55c \ub2e8\uc77c \ub274\ud074\ub808\uc624\ud2f0\ub4dc \ubcc0\uacbd\uc744 \uac00\ub2a5\ud558\uac8c \ud569\ub2c8\ub2e4. \uc885\uc885 ‘\uac80\uc0c9 \ubc0f \uad50\uccb4’ \ub3c4\uad6c\ub77c\uace0 \ubd88\ub9ac\ub294 \ud504\ub77c\uc784 \ud3b8\uc9d1\uae30\ub294 DSB\uc5d0 \uc758\uc874\ud558\uc9c0 \uc54a\uace0 12\uac00\uc9c0 \uac00\ub2a5\ud55c \uc5fc\uae30\uc30d \uce58\ud658\uacfc \ud45c\uc801\ud654\ub41c \uc791\uc740 \uc0bd\uc785 \ubc0f \uc0ad\uc81c\ub97c \uc218\ud589\ud560 \uc218 \uc788\ub294 \ub354 \ud070 \ub2e4\uc6a9\uc131\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ubc1c\uc804\uc740 \uc815\ubc00\ub3c4\ub97c \ud06c\uac8c \ud5a5\uc0c1\uc2dc\ud0a4\uace0 \ud45c\uc801 \uc678 \ud6a8\uacfc\uc758 \uc704\ud5d8\uc744 \uc904\uc785\ub2c8\ub2e4.<\/p>\n

\n
\n \"\ubbf8\ub798\n <\/div>
\n <\/span>
\n \ubbf8\ub798 \uc9c0\ud5a5\uc801\uc774\uace0 \ube5b\ub098\ub294 DNA \uc774\uc911 \ub098\uc120\uc774 \ucc9c\uc0c1\uc758 \ubc18\uc9dd\uc774\ub294 CRISPR-Cas9 \ubcf5\ud569\uccb4\uc5d0 \uc758\ud574 \uc815\ubc00\ud558\uac8c \ud3b8\uc9d1\ub418\uace0 \uc788\ub294 \ubaa8\uc2b5, \uc2e4\ud5d8\uc2e4 \ud658\uacbd\uc5d0\uc11c \uc815\ubc00\ub3c4\uc640 \ucca8\ub2e8 \uc0dd\uba85\uacf5\ud559\uc744 \uc0c1\uc9d5\ud569\ub2c8\ub2e4.
\n <\/span>
\n <\/figcaption><\/figure>\n<\/p>\n

\uce58\ub8cc\uc801 \ucd5c\uc804\uc120: \ub09c\uce58\ubcd1 \ud45c\uc801\ud654<\/strong><\/p>\n

CRISPR-Cas9\uc758 \uce58\ub8cc \uc7a0\uc7ac\ub825\uc740 \ubc29\ub300\ud558\uba70, \uadfc\ubcf8\uc801\uc778 \uc720\uc804\uc801 \uc6d0\uc778\uc744 \ud574\uacb0\ud568\uc73c\ub85c\uc368 \uc218\ub9ce\uc740 \ub09c\uce58\ubcd1\uc5d0 \uac78\uccd0 \uc788\uc2b5\ub2c8\ub2e4. DNA\ub97c \uc815\ubc00\ud558\uac8c \uc218\uc815\ud558\ub294 \uc774 \uae30\uc220\uc758 \ub2a5\ub825\uc740 \uc774\uc804\uc5d0 \ubd88\uce58\ubcd1\uc73c\ub85c \uac04\uc8fc\ub418\uc5c8\ub358 \uc9c8\ud658\uc744 \uce58\ub8cc\ud560 \uc218 \uc788\ub294 \uae38\uc744 \uc5f4\uc5b4\uc90d\ub2c8\ub2e4.<\/p>\n

    \n
  • \ub2e8\uc77c \uc720\uc804\uc790 \uc9c8\ud658:<\/strong> \ub2e8\uc77c \uc720\uc804\uc790 \uacb0\ud568\uc73c\ub85c \uc778\ud574 \ubc1c\uc0dd\ud558\ub294 \uc774\ub7ec\ud55c \uc9c8\ud658\uc740 \uc8fc\uc694 \ud45c\uc801\uc785\ub2c8\ub2e4. CRISPR-Cas9\ub294 \ud608\uc561 \uc904\uae30\uc138\ud3ec\ub97c \uc218\uc815\ud558\uc5ec \uac74\uac15\ud55c \ud5e4\ubaa8\uae00\ub85c\ube48 \ub610\ub294 \ud0dc\uc544 \ud5e4\ubaa8\uae00\ub85c\ube48\uc744 \uc0dd\uc0b0\ud568\uc73c\ub85c\uc368 \uc99d\uc0c1\uc744 \uc644\ud654\ud560 \uc218 \uc788\ub294 \uacb8\uc0c1 \uc801\ud608\uad6c \ube48\ud608(SCD) \ubc0f \ubca0\ud0c0 \uc9c0\uc911\ud574 \ube48\ud608\uacfc \uac19\uc740 \uc9c8\ud658\uc5d0 \ub300\ud574 \uc5c4\uccad\ub09c \uac00\ub2a5\uc131\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. 2023\ub144 12\uc6d4, SCD \ubc0f \uc218\ud608 \uc758\uc874\uc131 \ubca0\ud0c0 \uc9c0\uc911\ud574 \ube48\ud608\uc5d0 \ub300\ud55c \ucd5c\ucd08\uc758 \ubbf8\uad6d CRISPR \uce58\ub8cc\uc81c\uc778 Casgevy(exa-cel)\uc758 \uc2b9\uc778\uc740 \uc5ed\uc0ac\uc801\uc778 \uc774\uc815\ud45c\uac00 \ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uae30\ud0c0 \ud45c\uc801\uc73c\ub85c\ub294 \ub0ad\ud3ec\uc131 \uc12c\uc720\uc99d, \ud5cc\ud305\ud134\ubcd1, \uadf8\ub9ac\uace0 \uc810\uc9c4\uc801\uc778 \uc2dc\ub825 \uc800\ud558\ub97c \uc720\ubc1c\ud558\ub294 \ud76c\uadc0 \uc720\uc804 \uc9c8\ud658\uc778 \ub808\ubc84 \uc120\ucc9c\uc131 \ube44\uc9c4\ub2e8\uc131 \ubc31\ub0b4\uc7a5 10\ud615 \ub4f1\uc774 \uc788\uc73c\uba70, \uc774\uc5d0 \ub300\ud55c \uc784\uc0c1 \uc2dc\ud5d8\uc774 \uc9c4\ud589 \uc911\uc785\ub2c8\ub2e4.<\/li>\n
  • \uc554:<\/strong> CRISPR\ub294 \uba74\uc5ed \uc138\ud3ec(\uc608: CAR-T \uc138\ud3ec)\ub97c \uacf5\ud559\uc801\uc73c\ub85c \uac1c\uc870\ud558\uc5ec \uc554\uc138\ud3ec\ub97c \ub354 \uc798 \uc778\uc2dd\ud558\uace0 \ud30c\uad34\ud558\uac70\ub098 \uc885\uc591 \uc720\uc804\uc790\ub97c \ud30c\uad34\ud558\ub294 \ub370 \ud65c\uc6a9\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/li>\n
  • \uac10\uc5fc\ubcd1:<\/strong> HIV\uc640 \uac19\uc774 \ubc14\uc774\ub7ec\uc2a4 DNA\ub97c \ud45c\uc801\uc73c\ub85c \uc0bc\uc544 \uc138\ud3ec\ub97c \uac10\uc5fc\uc5d0 \uc800\ud56d\ud558\ub3c4\ub85d \uacf5\ud559\uc801\uc73c\ub85c \uac1c\uc870\ud558\ub824\ub294 \ub178\ub825\uc774 \uc9c4\ud589 \uc911\uc785\ub2c8\ub2e4. \ud55c \uc0ac\ub840 \uc5f0\uad6c\uc5d0\uc11c\ub294 HIV \ud658\uc790\uc758 CCR5 \uacb0\ud54d \uc870\ud608\ubaa8\uc138\ud3ec \ubc0f \uc804\uad6c\uc138\ud3ec\ub97c \uacf5\ud559\uc801\uc73c\ub85c \uac1c\uc870\ud558\uae30 \uc704\ud574 CRISPR\ub97c \uc131\uacf5\uc801\uc73c\ub85c \uc0ac\uc6a9\ud588\uc9c0\ub9cc, \ud6a8\uc728\uc131 \uac1c\uc120\uc774 \ud544\uc694\ud569\ub2c8\ub2e4.<\/li>\n
  • \uc2e0\uacbd\ud1f4\ud589\uc131 \uc9c8\ud658:<\/strong> \ub1cc \uc804\ub2ec\uc774 \ub354 \uc5b4\ub835\uc9c0\ub9cc, CRISPR \uc5f0\uad6c\ub294 \ud5cc\ud305\ud134\ubcd1, \uc54c\uce20\ud558\uc774\uba38\ubcd1, \ud30c\ud0a8\uc2a8\ubcd1\uacfc \uac19\uc740 \uc9c8\ud658\uc744 \uc720\ubc1c\ud558\ub294 \ub3cc\uc5f0\ubcc0\uc774\ub97c \uad50\uc815\ud558\ub294 \uac83\uc744 \ubaa9\ud45c\ub85c \ud569\ub2c8\ub2e4.<\/li>\n
  • \uc2ec\ud608\uad00 \uc9c8\ud658:<\/strong> \uc2ec\uc7a5 \uc9c8\ud658\uc758 \uc704\ud5d8\uc744 \uc904\uc774\uae30 \uc704\ud574 \ub192\uc740 \ucf5c\ub808\uc2a4\ud14c\ub864(\uc608: PCSK9, ANGPTL3, Lp(a))\uacfc \uad00\ub828\ub41c \uc720\uc804\uc790\ub97c \ud45c\uc801\uc73c\ub85c \ud558\ub294 \uc784\uc0c1 \uc2dc\ud5d8\uc774 \uc9c4\ud589 \uc911\uc785\ub2c8\ub2e4. \uac00\uc871\uc131 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864\ud608\uc99d\uc5d0 \ub300\ud55c Verve Therapeutics\uc758 CRISPR \uae30\ubc18 \uce58\ub8cc\uc81c\uac00 \uc8fc\ubaa9\ud560 \ub9cc\ud55c \uc608\uc785\ub2c8\ub2e4.<\/li>\n
  • \ud76c\uadc0 \ub300\uc0ac \uc9c8\ud658:<\/strong> 2025\ub144 5\uc6d4\uc758 \ud68d\uae30\uc801\uc778 \uc131\uacfc\ub294 6\uac1c\uc6d4 \ub9cc\uc5d0 \uac1c\ubc1c \ubc0f \ud22c\uc5ec\ub41c \ud76c\uadc0 \ub300\uc0ac \uc9c8\ud658\uc778 \uc911\uc99d \uce74\ub974\ubc14\ubaa8\uc77c \ud3ec\uc2a4\ud398\uc774\ud2b8 \ud569\uc131\ud6a8\uc18c 1(CPS1) \uacb0\ud54d\uc99d\uc744 \uc553\ub294 \uc601\uc544(KJ)\uc5d0 \ub300\ud55c \ucd5c\ucd08\uc758 \uac1c\uc778 \ub9de\ucda4\ud615 CRISPR \uce58\ub8cc\uc81c\uc600\uc2b5\ub2c8\ub2e4.<\/li>\n<\/ul>\n
    \n
    \n \"\ub2e4\uc591\ud55c\n <\/div>
    \n <\/span>
    \n \ub2e4\uc591\ud55c \ud76c\uadc0 \uc9c8\ud658(\uc608: \uacb8\uc0c1 \uc801\ud608\uad6c, \uc554\uc138\ud3ec, \ub274\ub7f0)\uc744 \ub098\ud0c0\ub0b4\ub294 \ub2e4\uc591\ud55c \ud604\ubbf8\uacbd \uc138\ud3ec \uc138\ud2b8\uac00 \ube5b\ub098\ub294 \ud604\ubbf8\uacbd \uc720\uc804\uc790 \ud3b8\uc9d1 \ub3c4\uad6c\uc5d0 \uc758\ud574 \uac1c\ubcc4\uc801\uc73c\ub85c \ud45c\uc801\ud654\ub418\uace0 \uad50\uc815\ub418\ub294 \ubaa8\uc2b5, \uad11\ubc94\uc704\ud55c \uce58\ub8cc \ubc94\uc704\ub97c \ubcf4\uc5ec\uc90d\ub2c8\ub2e4.
    \n <\/span>
    \n <\/figcaption><\/figure>\n<\/p>\n

    \uc0c1\uc6a9\ud654 \uc804\ub7b5: \ud601\uc2e0\uacfc \uc2dc\uc7a5 \uc5ed\ud559\uc758 \uad50\ucc28\uc810 \ud0d0\uc0c9<\/strong><\/p>\n

    \ud68d\uae30\uc801\uc778 \uacfc\ud559\uc801 \ubc1c\uacac\uc5d0\uc11c \uc804 \uc138\uacc4\uc801\uc73c\ub85c \uc811\uadfc \uac00\ub2a5\ud55c \uc0c1\uc5c5\uc801 \uce58\ub8cc\uc81c\ub85c \ub098\uc544\uac00\ub294 \uc5ec\uc815\uc740 \ubcf5\uc7a1\uc131\uc73c\ub85c \uac00\ub4dd\ud569\ub2c8\ub2e4. CRISPR-Cas9\uc758 \uacbd\uc6b0, \uc774 \uacbd\ub85c\ub294 \uc5f0\uad6c \uac1c\ubc1c, \uc81c\uc870, \uc9c0\uc801 \uc7ac\uc0b0\uad8c, \uc2dc\uc7a5 \uc811\uadfc \ubc0f \uc724\ub9ac\uc801 \uace0\ub824 \uc0ac\ud56d\uc744 \ub2e4\ub8e8\ub294 \ub2e4\uac01\uc801\uc778 \uc811\uadfc \ubc29\uc2dd\uc774 \ud544\uc694\ud569\ub2c8\ub2e4.<\/p>\n

    1. \uc5f0\uad6c \uac1c\ubc1c \ubc0f \uc784\uc0c1 \uc2dc\ud5d8: \uc5c4\uaca9\ud55c \uacbd\ub85c<\/h3>\n

    CRISPR \uce58\ub8cc\uc81c\ub97c \uac1c\ubc1c\ud558\ub824\uba74 \uad11\ubc94\uc704\ud55c \uc804\uc784\uc0c1 \ubc0f \uc784\uc0c1 \uac80\uc99d\uc774 \ud544\uc694\ud569\ub2c8\ub2e4. \ud2b9\ud788 \uc720\uc804\uc790 \ud3b8\uc9d1 \uce58\ub8cc\uc81c\uc758 \uacbd\uc6b0 \uaddc\uc81c \uacbd\ub85c\ub294 \uc5c4\uaca9\ud569\ub2c8\ub2e4.<\/p>\n

      \n
    • \uc804\uc784\uc0c1 \ud3c9\uac00:<\/strong> \uc778\uac04 \uc784\uc0c1 \uc2dc\ud5d8 \uc804\uc5d0 \uce58\ub8cc\ubc95\uc740 \uc548\uc804\uc131\uacfc \ud6a8\ub2a5\uc744 \ud3c9\uac00\ud558\uae30 \uc704\ud574 \uc5c4\uaca9\ud55c \uccb4\uc678<\/em> \ubc0f \uccb4\ub0b4<\/em> \uc5f0\uad6c\ub97c \uac70\uce58\uba70, \uc774\ub294 \uc784\uc0c1 \uc2dc\ud5d8 \uc2e0\uc57d(IND) \uc2e0\uccad\uc758 \uae30\ucd08\ub97c \ud615\uc131\ud569\ub2c8\ub2e4.<\/li>\n
    • \uc784\uc0c1 \ub2e8\uacc4(I, II, III):<\/strong> \uc774\ub7ec\ud55c \uc784\uc0c1 \uc2dc\ud5d8\uc740 \uc810\ucc28 \ub354 \ud070 \ud658\uc790 \uc9d1\ub2e8\uc5d0\uc11c \uc548\uc804\uc131, \ub0b4\uc57d\uc131 \ubc0f \ud6a8\ub2a5\uc744 \uc21c\ucc28\uc801\uc73c\ub85c \ud3c9\uac00\ud569\ub2c8\ub2e4. 1\ub2e8\uacc4\ub294 \uc548\uc804\uc131\uc5d0 \uc911\uc810\uc744 \ub450\uace0, 2\ub2e8\uacc4\ub294 \ud6a8\ub2a5 \ubc0f \ubd80\uc791\uc6a9\uc5d0 \uc911\uc810\uc744 \ub450\uba70, 3\ub2e8\uacc4\ub294 \ud45c\uc900 \uce58\ub8cc\ubc95\uc5d0 \ub300\ud55c \ud6a8\ub2a5\uc744 \ud655\uc778\ud569\ub2c8\ub2e4. \uc774 \uacfc\uc815\uc740 \uac70\uc758 10\ub144\uc774 \uac78\ub9b4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/li>\n
    • \uaddc\uc81c \uae30\uad00:<\/strong> \ubbf8\uad6d \uc2dd\ud488\uc758\uc57d\uad6d(FDA) \ubc0f \uc720\ub7fd\uc758\uc57d\ud488\uccad(EMA)\uacfc \uac19\uc740 \uae30\uad00\uc740 \uc5c4\uaca9\ud55c \uc9c0\uce68\uc744 \uc2dc\ud589\ud569\ub2c8\ub2e4. \uc77c\uad00\ub41c \uc81c\ud488 \ud488\uc9c8\uacfc \uc548\uc804\uc131\uc744 \ubcf4\uc7a5\ud558\uae30 \uc704\ud574 \ud3ec\uad04\uc801\uc778 \ud654\ud559, \uc81c\uc870 \ubc0f \uad00\ub9ac(CMC) \ubb38\uc11c\ub97c \uc694\uad6c\ud569\ub2c8\ub2e4.<\/li>\n
    • \uc7a5\uae30 \ucd94\uc801 \uad00\ucc30:<\/strong> \uc720\uc804\uc790 \ud3b8\uc9d1\uc758 \uc7a0\uc7ac\uc801\uc73c\ub85c \uc601\uad6c\uc801\uc778 \ud2b9\uc131\uc73c\ub85c \uc778\ud574, \uaddc\uc81c \uae30\uad00\uc740 \uc7a5\uae30\uc801\uc778 \uc548\uc804\uc131, \ud6a8\ub2a5 \ubc0f \uc7a0\uc7ac\uc801\uc778 \ud45c\uc801 \uc678 \ud6a8\uacfc\ub97c \ubaa8\ub2c8\ud130\ub9c1\ud558\uae30 \uc704\ud574 \uc2dc\ud310 \ud6c4 \ucd5c\ub300 15\ub144\uc758 \uac10\uc2dc\ub97c \uc694\uad6c\ud558\ub294 \uacbd\uc6b0\uac00 \ub9ce\uc2b5\ub2c8\ub2e4.<\/li>\n
    • \uc2e0\uc18d \uc2ec\uc0ac \ud504\ub85c\uadf8\ub7a8:<\/strong> \ud76c\uadc0\ud558\uace0 \uc0dd\uba85\uc744 \uc704\ud611\ud558\ub294 \uc9c8\ubcd1\uc758 \uacbd\uc6b0, FDA\ub294 \uac1c\ubc1c \ubc0f \uac80\ud1a0\ub97c \uac04\uc18c\ud654\ud558\uc5ec \ud658\uc790 \uc811\uadfc\uc744 \uac00\uc18d\ud654\ud558\uae30 \uc704\ud574 \uc2e0\uc18d \uc2ec\uc0ac \ud504\ub85c\uadf8\ub7a8(\ud328\uc2a4\ud2b8 \ud2b8\ub799, \ud601\uc2e0 \uc2e0\uc57d, \uac00\uc18d \uc2b9\uc778, \uc6b0\uc120
      \n","protected":false},"excerpt":{"rendered":"

      \ubb34\ud55c\ud55c \uac00\ub2a5\uc131\uc744 \ud488\uace0 \ub04a\uc784\uc5c6\uc774 \uc9c4\ud654\ud558\ub294 \uc0dd\uba85\uacf5\ud559 \ud601\uc2e0\uc758 \uc9c0\ud3c9\uc5d0\uc11c, \ub2e8\uc21c\ud55c \uacfc\ud559\uc801 \uc9c4\ubcf4\ub97c \ub118\uc5b4 \uc778\ub958\uc758 \uc0c8\ub85c\uc6b4 \uc2dc\ub300\ub97c \uc608\uace0\ud558\ub294 \uae30\ub150\ube44\uc801\uc778 \uc0ac\uac74\ub4e4\uc774 \uc788\uc2b5\ub2c8\ub2e4. CRISPR-Cas9 \uc720\uc804\uc790 \ud3b8\uc9d1 \uae30\uc220\uc740 \ubc14\ub85c \uadf8\ub7ec\ud55c \uac70\ub300\ud55c \ub3c4\uc57d \uc911 \ud558\ub098\ub85c, \uc815\ubc00 \uc758\ud559 \ubd84\uc57c\uc758 ‘\ud000\ud140 \uc81c\ub124\uc2dc\uc2a4’\ub97c \uc5f4\uba70 \ub09c\uce58\ubcd1\uacfc\uc758 \uc2f8\uc6c0 \ubc29\uc2dd\uc744 \uc644\uc804\ud788 \uc7ac\uc815\uc758\ud560 \uac83\uc744 \uc57d\uc18d\ud569\ub2c8\ub2e4. \uad6c\uae00 \uae00\ub85c\ubc8c \uac80\uc0c9 \uc2dc\uc7a5\uc758 \uc218\uc11d \ube44\uc988\ub2c8\uc2a4 \ubd84\uc11d\uac00\uc774\uc790 \uc791\uac00\ub85c\uc11c, \uc800\ub294 ‘\ubca0\uc2a4\ud3a0\ub77c \ub125\uc11c\uc2a4’\uc758 ‘\uc790\uc728 \uc544\uce74\uc774\ube0c’ […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-623","post","type-post","status-publish","format-standard","hentry","category-1"],"_links":{"self":[{"href":"https:\/\/www.vespellar.com\/blog\/wp-json\/wp\/v2\/posts\/623","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.vespellar.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.vespellar.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.vespellar.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vespellar.com\/blog\/wp-json\/wp\/v2\/comments?post=623"}],"version-history":[{"count":0,"href":"https:\/\/www.vespellar.com\/blog\/wp-json\/wp\/v2\/posts\/623\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.vespellar.com\/blog\/wp-json\/wp\/v2\/media?parent=623"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.vespellar.com\/blog\/wp-json\/wp\/v2\/categories?post=623"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vespellar.com\/blog\/wp-json\/wp\/v2\/tags?post=623"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}